ea0073aep602 | Reproductive and Developmental Endocrinology | ECE2021
Kraoua Lilia
, Fredj Hana
, Adhoum Cyrine
, Achour Ahlem
, Maazoul Faouzi
, Trabelsi Mediha
, Mrad Ridha
IntroductionPremature ovarian insufficiency (POI) is defined by menstrual disturbance (oligomenorrhea or amenorrhea) before 40 years and confirmed by two FSH levels in the menopausal range, obtained at least a month apart. Some POI cases are syndromic such as Turner’s syndrome or Blepharophimosis–Ptosis–Epicanthus inversus Syndrome type 1 (BPES). BPES type 1 (MIM: 110100) is a rare autosomal dominant syndrome caused by mutations in FOX...